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Latest Updates
July 2005 Combination Trial Updates and Additions
Protocol ID
|
Trial Title
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A Phase I Dose Escalation Trial of Targretin and Ontak in Patients with Hematologic Malignancies |
| NH-0139, NCI-V01-1681 |
Phase II Study of Docetaxel, Estramustine, and Thalidomide in Patients with Hormone-Refractory Prostate Cancer |
| CWRU-1301; NCI-5389; CWRU-050212 |
Phase I Study of Erlotinib, Docetaxel, and Radiotherapy in Patients with Locally Advanced Squamous Cell Cancer of the Head and Neck |
| JHOC-J0220, JHOC-02072506, NCI-5869, CDR0000301882 |
A Phase I Clinical Trial of Erlotinib, Fluorouracil, Leucovorin Calcium, and Oxaliplatin (FOLFOX-4) in Patients with Metastatic or Locally Advanced Colorectal Cancer |
| MSKCC-03031; NCI-5441 |
A Phase I Clinical Trial of Erlotinib, Gemcitabine, and Radiotherapy in Patients with Locally Advanced Unresectable Pancreatic Cancer |
| CTRC-IDD-0135; NCI-5439 |
Phase I Study of Erlotinib, Trastuzumab (Herceptin), and Paclitaxel in Patients with Advanced Solid Tumors |
| OSU-02H0084; OSU-0213; NCI-5393 |
Phase I/II Study of Erlotinib and Docetaxel in Patients with Locally Advanced, Metastatic, or Recurrent Squamous Cell Carcinoma of the Head and Neck |
| NCCTG-N0177 |
A Dose-Escalation, Phase I/II Clinical Trial of Erlotinib and Radiotherapy in Patients with Glioblastoma Multiforme |
| NYU-0230, NCI-5886, NYU-1102-590, NYWCCC-NYU-0230 |
Phase I/II Study of Erlotinib, Carboplatin, and Paclitaxel in Patients with Stage III or IV Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Carcinoma |
| NCCTG-N0234 |
Phase II Study of Erlotinib and Gemcitabine in Patients with Metastatic Breast Cancer Previously Treated with Anthracycline and/or Taxane |
| UCLA-0106020, GENENTECH-OSI2365s, NCI-G02-2057 |
Phase I/II Study of Trastuzumab (Herceptin) and Erlotinib as First-Line Therapy in Women with Metastatic Breast Cancer Associated with HER-2/neu Overexpression |
| NCI-03-C-0085 |
Phase III randomized study of operative debulking and systemic chemotherapy with or without intra- and peri-operative intraperitoneal chemotherapy in patients with peritoneal carcinomatosis from low-grade gastrointestinal adenocarcinoma |
| FRE-GERCOR-GEM-GEMOX/D00-3, EU-20324 |
Phase III randomized study of gemcitabine with or without oxaliplatin in patients with locally advanced or metastatic unresectable pancreatic adenocarcinoma |
| MSKCC-03078, LILLY-H3E-US-JMGA, CDR0000339681 |
Phase II Clinical Trial of Neoadjuvant Pemetrexed and Cisplatin Followed by Extrapleural Pneumonectomy and Radiotherapy in Patients with Stage I, II, or III Pleural Mesothelioma |
| 5141 |
A Phase II Clinical Trial of Pemetrexed Combined with Gemcitabine in Metastatic Breast Cancer Patients After Taxane Therapy |
| 7221 |
A Phase I/II Clinical Trial of Biweekly Pemetrexed and Gemcitabine in Patients with Advanced Cancer |
| 7213 |
Pemetrexed Combined with Gemcitabine for Chemotherapy-Naive Patients with Locally Advanced or Metastatic Non-Small Cell Lung Cancer |
| 7214 |
Pemetrexed Combined with Gemcitabine for Patients with Malignant Pleural or Peritoneal Mesothelioma Who Have Not Had Previous Chemotherapy |
| NCCTG-N014A |
Phase II Study of Oxaliplatin, Fluorouracil, Leucovorin Calcium, and Cetuximab in Patients with Unresectable Hepatic Metastases Secondary to Metastatic Colorectal Adenocarcinoma |
| ECOG-E8200 |
Phase II Randomized Study of Irinotecan and Docetaxel with or Without Cetuximab in Patients with Metastatic Adenocarcinoma of the Pancreas |
| EORTC-21011 |
A randomized, open-label, multicenter, phase III clinical trial of ultraviolet A light therapy with methoxsalen with or without bexaretene in patients with mycosis fungoides |
| UCLA-0306083, CDR0000335434 |
A Phase I Clinical Trial of Celecoxib and Erlotinib in Patients with Stage IIIb or IV Non-Small Cell Lung Cancer |
| LIGAND-L1069-49 (SPIRIT I) |
Randomized Phase III Trial Comparing Targretin Capsules, Cisplatin and Vinorelbine Against Cisplatin and Vinorelbine in Chemotherapy-Naive Patients with Advanced or Metastatic Non-Small Cell Lung Cancer |
| LIGAND-L1069-48, BMC-C-7093-49, UCLA-0301086 (SPIRIT II) |
A Randomized Phase III Clinical Trial of Carboplatin and Paclitaxel with Bexarotene Versus Carboplatin and Paclitaxel Alone in Patients with Chemotherapy-Naive Stage IIIB or IV Non-Small Cell Lung Cancer |
| DFCI-03083, SPORE trial |
Phase II Randomized Trial of Low-Dose Cyclophosphamide and Methotrexate with or Without Bevacizumab in Women with Metastatic Breast Cancer |
| 2003-0520 |
A Non-Randomized, Open Label, Active Control, Phase II Clinical Trial (protocol ID: 2003-0520) of Bevacizumab and Rituximab in Patients with Relapsed and Chemotherapy or Rituxan-Refractory Aggressive B-cell Non-Hodgkin’s Lymphoma |
| CA225014, BMS-014, EXPLORE • FOLFOX-4 |
A Randomized Phase III Clinical Trial of Cetuximab in Combination with 5-Fluorouracil (5-FU)/Leucovorin/Oxaliplatin (FOLFOX-4) as a Second Line Treatment in Patients with Metastatic, EGFr-positive Colorectal Cancer |
| EORTC-10021, IDBBC-10021 |
A Randomized, Double-Blind, Placebo-Controlled, Phase II Clinical Trial pf Anastrozole Monotherapy or in Combination with Gefitinib in Postmenopausal Women with Metastatic or Locally Recurrent Breast Cancer |
| ECOG-4101 |
A Randomized, Open-Label, Phase II Clinical Trial of Anastrozol and Gefitinib Compared to Fulvestrant and Gefitinib in Postmenopausal Women with Recurrent or Metastatic Hormone Receptor-Positive Breast Cancer |
| ZD1839US/0713, NCT00077025 |
A Randomized, Double-Blind, Placebo Controlled, Phase II Clinical Trial of Anastrozole with Placebo Compared to Anastrozole with Gefitinib in Postmenopausal Patients with Estrogen Receptor and/or Progesterone Receptor Metastatic Breast Cancer |
| DMS-0236, ZENECA-IRUSIRES0162 |
A Randomized, Double-Blind, Placebo-Controlled, Phase II Clinical Trial of Gefitinib with or Without Tamoxifen in Patients with Tamoxifen-Resistant Metastatic Breast Cancer |
| VICC-BRE-0249 |
A Randomized Phase II Pilot Clinical Trial of Gefitinib Followed By Local Surgery in Women with Ductal Carcinoma In Situ of the Breast |
| ZD1839IL/0225, NCT00069290 |
A Phase II Clinical Trial of Tamoxifen (20 Mg) and Gefitinib (250 Mg) Compared to Tamoxifen (20 Mg) and Placebo in Patients with Estrogen Receptor and/or Progesterone Positive Metastatic Breast Cancer |
| NCI-04-C-0141, NCI-5926 |
A Pilot, Dose-Escalation, Phase I Clinical Trial of Gefitinib, Paclitaxel, and Radiotherapy in Patients with Advanced or Recurrent Squamous Cell Carcinoma of the Head and Neck |
| CDR0000370806, SWOG-S0342 |
A Randomized Phase II Clinical Trial of Concurrent Versus Sequential Paclitaxel, Carboplatin and Cetuximab in Patients with Stage IIIb or IV Non-Small Cell Lung Cancer |
| CDR0000365614, MSKCC-04006 |
A Non-Randomized, Open-Label, Pilot, Phase II Clinical Trial of Neoadjuvant Cetuximab, Fluorouracil, and Pelvic Irradiation in Patients with Locally Advanced or Locally Recurrent Rectal Cancer |
| CDR0000360850, RTOG-0234 |
A Randomized Phase II Clinical Trial of Adjuvant Cetuximab and Chemoradiotherapy Using Either Cisplatin or Docetaxel in Patients with Resected Stage III or IV Squamous Cell Carcinoma or Lymphoepithelioma of the Head and Neck |
| GOG-0146P, BMS-CA225-019 |
A Phase II Clinical Trial of Cetuximab and Carboplatin in Patients with Recurrent, Platinum-Sensitive, Ovarian Epithelial or Primary Peritoneal Cancer |
| MSKCC-04021, NCI-6447 |
A Non-Randomized, Open-Label, Phase II Clinical Trial of Bevacizumab, Irinotecan and Cisplatin in Patients with Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma |
| CWRU-3100, NCI-2722, CDR0000069090 |
A Phase II Clinical Trial of Neoadjuvant Docetaxel with or Without Bevacizumab in Patients with Locally Unresectable, Advanced Breast Cancer |
| DFCI-02025, NCI-5642 |
A Phase I Clinical Trial of Neoadjuvant Bevacizumab, 5-Fluououracil, and Radiation Therapy Followed by Surgery in Patients with Primary and Non-Metastatic Rectal Cancer |
ICCG-C/14/96; EU-20040
|
Phase III Trial of Adjuvant Epirubicin with or Without Docetaxel and Concurrent or Sequential Tamoxifen in Postmenopausal Women with Node-Positive Breast Cancer |
SWS-SAKK-43/99; EU-99042
|
Phase III Randomized Trial of Preoperative Compared to Postoperative Chemotherapy with Docetaxel, Cisplatin, and Fluorouracil in Patients with Locally Advanced Operable Gastric Carcinoma |
| ID01-580, NCT00050167 |
Phase III Trial Evaluating the Differing Taxanes/Taxane Combinations on the Outcomes of Patients with Operable Breast Cancer |
| CWRU-LILY-1503; LILLY-B9E-US-S245 |
Phase III Randomized Trial of Gemcitabine and Carboplatin Followed By Immediate Docetaxel Compared with Delayed Docetaxel in Patients with Stage IIIB or IV Non-Small Cell Lung Cancer |
| UCLA-9911084; AVENTIS-GIA-11156; GENENTECH-H2269s |
Phase III Randomized Trial of Neoadjuvant Docetaxel and Carboplatin with or Without Trastuzumab (Herceptin) in Women with Locally Advanced Breast Cancer |
| FRE-FNCLCC-GETUG-12/0203; EU-20238 |
Phase III Randomized Trial of Neoadjuvant Releasing Factor Agonist Therapy and Antiandrogen Therapy with or Without Docetaxel And Estramustine in Patients with Locally Advanced Prostate Cancer or with A High Risk of Relapse |
| SWOG-S0205, CDR0000347414 |
A Phase III Randomized Clinical Trial of Gemcitabine with and Without Cetuximab as First-Line Therapy in Patients with Locally Advanced Unresectable or Metastatic Adenocarcinoma of the Pancreas |
| EORTC-10994; ACCOG-EORTC-10994; SAKK-EORTC-10994; SBGC-EORTC-10994 |
Phase III Randomized Trial of Neoadjuvant Fluorouracil, Epirubicin, and Cyclophosphamide Versus Neoadjuvant Docetaxel and Epirubicin Followed By Radiotherapy and Surgery in Women with Locally Advanced, Inflammatory, or Large Operable Breast Cancer |
| LMU-ADEBAR; EU-20221 |
Phase III Randomized Trial of Fluorouracil, Epirubicin, and Cyclophosphamide Versus Docetaxel, Epirubicin, and Cyclophosphamide in Women with Primary Breast Cancer |
| Dox-2a-07; NCT00082472 |
Inhaled Doxorubicin Plus IV Docetaxel and Cisplatin in Patients with Non-Small-Cell Lung Carcinoma (NSCLC) |
| CHNMC-03049; ZENECA-1839US/0274; ZENECA-IRUSIRES0012 |
Phase I/II Trial of Gefitinib, Trastuzumab (Herceptin), and Docetaxel in Patients with HER2/neu-Overexpressing Metastatic Adenocarcinoma of the Breast |
| 2938 |
A Phase III Clinical Trial of Pemetrexed and Cisplatin Compared to Gemcitabine and Cisplatin in Patients with Locally Advanced or Metastatic Non-Small Cell Lung Cancer |
| 7216 |
A Phase II Clinical Trial of Pemetrexed and Cisplatin Followed by Surgery and Radiation in Patients with Pleural Mesothelioma |
| UCLA-0308082; AVENTIS-GIA-16115; GENENTECH-OSI-2527S |
Phase II Trial of Docetaxel and Erlotinib in Older Patients with Progressive Hormone Refractory Prostate Cancer |
| NCI-04-C-0132 |
Phase II Trial of Docetaxel, Estramustine, and Thalidomide in Patients with Androgen-Independent Metastatic Adenocarcinoma of the Prostate |
| MSKCC-03076 |
Phase II Trial of Rapid Hormonal Cycling with Testosterone and Leuprolide in Combination with Docetaxel in Patients with Recurrent or Non-Castrate Metastatic Adenocarcinoma of the Prostate |
| FCCC-03003 |
Phase II Randomized Trial of Bevacizumab with or Without Docetaxel in Patients with Previously Treated Metastatic Pancreatic Adenocarcinoma |
| ID02-668; NCT00076310 |
A Nonrandomized, Open Label, Uncontrolled, Single Group Assignment, Phase II Clinical Trial of Erlotinib, Cisplatin and Docetaxel in Patients with Head and Neck Squamous Cell Cancer |
| SWOG-S0215 |
Phase II Pilot Trial of Trastuzumab (Herceptin), Docetaxel, and Vinorelbine with Filgrastim (G-CSF) Support in Women with HER2-Positive Stage IV Breast Cancer |
| MSKCC-04003 |
Phase I Trial of Gefitinib and Docetaxel in Patients with Advanced Solid Tumors |
| NCCTG-N0432 |
Phase II Trial of Docetaxel, Capecitabine, and Bevacizumab as First-Line Chemotherapy in Patients with Metastatic Breast Cancer |
| NCI-02-C-0149 |
Phase I Trial of Ketoconazole and Docetaxel in Patients with Metastatic Androgen-Independent Prostate Cancer |
| UCCRC-11432B, NCI-5411, CDR0000069474 |
Phase I Trial of Erlotinib and Radiotherapy Plus Either Cisplatin, Etoposide, and Docetaxel or Carboplatin and Paclitaxel in Patients with Inoperable Stage III Non-Small Cell Lung Cancer |
| RPCI-RPC-0207, ZENECA-1839US/0295 |
A Dose-Escalation, Phase I Clinical Trial of Calcitriol and Gefitinib with or without Dexamethasone in Patients with Advanced Solid Tumors |
| ECOG-E1302, CTSU |
A Randomized, Placebo-Controlled, Double-Blind, Multicenter, Phase III Clinical Trial of Docetaxel with or without Gefitinib in Patients with Metastatic or Locally Recurrent Squamous Cell Carcinoma of the Head and Neck |
| RPCI-I-17403, ZENECA-IRUSIRES0414 |
A Phase I/II Clinical Trial of Capecitabine, Oxaliplatin, and Gefitinib in Patients with Metastatic Colorectal Cancer |
| MSKCC-04010 |
A Phase I/II Clinical Trial of Everolimus and Gefitinib in Patients with Progressive Glioblastoma Multiforme or Progressive Castrate Metastatic Prostate Cancer |
| DUMC-4939-03-6R0, VAMC-DURHAM-00813, DUMC-4939-04-6R1 |
An Open-Label, Dose-Escalation, Phase I Clinical Trial of Celecoxib and Gefitinib in Patients who are Former Smokers with Stage IIIb Or IV, Recurrent or Progressive Non-Small Cell Lung Cancer |
| ID99-146 |
A Phase III Clinical Trial of Neoadjuvant Therapy with Paclitaxel and Anthracycline-Containing Chemotherapy [Fluorouracil, Epirubicin, and Cyclophosphamide (FEC)] with or Without Trastuzumab in Patients with HEr2 Positive Breast Cancer |
| CALGB-80303 (CTSU) |
A Randomized, Double-Blind, Placebo-Controlled, Phase III Clinical Trial of Gemcitabine Alone and in Combination with Bevacizumab in Patients with Locally Advanced or Metastatic Adenocarcinoma of the Pancreas |
| 040257, 04-C-0257, NCI-04-C-0257 |
A Phase II Clinical Trial of Docetaxel, Thalidomide, Prednisone and Bevacizumab in Previously Untreated Patients with Androgen-Independent Prostate Cancer |
| ML17771, NCT00087620 |
An Open-Label, Randomized Phase III Trial of Capecitabine In Combination with Docetaxel or Capecitabine Followed by Docetaxel As First-Line Treatment For Metastatic Breast Cancer. |
| CDR0000069196; SWS-SAKK-16/00; EU-20138, NCT00030771 |
Phase III Trial of Neoadjuvant Docetaxel and Cisplatin with or Without Radiotherapy in Patients with Non-Small Cell Lung Cancer and Mediastinal Lymph Node Metastases |
| CDR0000068897; MDA-ID-00156; NCI-3410, NCT00024167 |
Randomized Phase III Trial to Compare the Effectiveness of Chemotherapy with or Without Strontium-89 in Treating Patients Who Have Prostate Cancer That Has Spread to the Bone. |
| ECOG-E2303 |
A Phase II Clinical Trial of Neoadjuvant Induction Therapy Comprising of Cetuximab, Paclitaxel, and Carboplatin Followed by Chemoradiotherapy Comprising of Cetuximab, Paclitaxel, Carboplatin, and Radiotherapy in Patients with Stage III or IV Operable Squamous Cell Cancer of the Head and Neck |
| CAN-NCIC-PR7, CAN-NCIC-JPR7, SWOG-JPR7 |
Phase III Randomized Trial of Intermittent Compared to Continuous Androgen Suppression in Patients with Prostate-Specific Antigen Progression in the Clinical Absence of Distant Metastases After Prior Radiotherapy for Prostate Cancer |
| CAN-NCIC-PR3, EU-99013, ISRCTN24991896, NCI-T94-0110O, CALGB-9593, ECOG-JPR03, MRC-PR07, SWOG-JPR3 |
Phase III Randomized Trial of Total Androgen Blockade with or Without Pelvic Irradiation in Patients with Locally Advanced Adenocarcinoma of the Prostate |
| MDA-2003-0922, NCI-6459 |
Phase II Randomized Trial of Hormonal Ablative Therapy, Doxorubicin, and Zoledronate with or Without Strontium Chloride Sr 89 in Patients with Androgen-Dependent Prostate Cancer and Bone Metastases |
| BC-PR-6 |
Phase II Trial of Antineoplastons A10 and AS2-1 Capsules with Total Androgen Blockade in Patients with Stage III or IV Adenocarcinoma of the Prostate |
| CALGB-99809 |
Phase II Trial of Androgen-Suppression Therapy Combined with External-Beam Radiotherapy and Boost Brachytherapy in Patients with Intermediate-Risk Localized Prostate Cancer |
| CALGB-99811 |
Phase II Trial of Neoadjuvant Paclitaxel, Estramustine, Carboplatin, and Androgen Ablation Followed By Radiotherapy in Patients with Poor-Prognosis Locally Advanced Prostate Cancer |
| 00-5891, NCT00041470 |
Phase I/II Trial of Navelbine (Vinorelbine), Taxol (Paclitaxel), Herceptin (Trastuzumab) and Neupogen (Filgrastim) in Stage IV Breast Cancer |
| UNC-LCCC-0310, UNC-GCRC-2102-ORC |
Phase II Trial of Multiepitope Autologous Dendritic Cell Vaccine, Trastuzumab, and Vinorelbine in Women with Locally Recurrent or Metastatic Breast Cancer |
| UCCRC-NCI-6580, NCI-6580, UCCRC-13200A |
A Randomized, Multicenter, Phase II Clinical Trial of Bevacizumab and Gemcitabine with Cetuximab Versus Erlotinib in Patients with Advanced Adenocarcinoma of the Pancreas |
| RPCI-PH-04603, ZENECA-IRUSIRES0303, RPCI-I-04603 |
A Phase I/II Clinical Trial of Oxaliplatin and Gefitinib in Combination with Radiotherapy in Patients with Locally Advanced or Metastatic Adenocarcinoma or Squamous Cell Carcinoma of the Esophagus or Gastroesophageal Junction |
| UCLA-0109030-03, TORI B-03, Western IRB #20041069, UCLA IRB #01-09-030 |
A Phase I/II Clinical Trial of Bevacizumab and Trastuzumab in Women with Relapsed or Metastatic Her2/Neu Overexpressing Adenocarcinoma of the Breast |
| IMCL-0452, CP02-0452 |
A Multicenter, Open-Label, Randomized, Phase III Clinical Trial of Docetaxel or Pemetrexed with or Without Cetuximab in Patients with Recurrent or Progressive Non-Small Cell Lung Cancer |
| CA225006, NCT00063141 |
A Randomized, Open-Label, Active Control, Parallel Assignment, Multicenter, Phase III Clinical Trial of Irinotecan and Cetuximab Compared to Irinotecan as Second-Line Treatment in Patients with Metastatic, EGFr-Positive Colorectal Cancer |
| MSKCC-99085, CWRU-LILY-1599, LILLY-H3E-MC-JMCH(a), NCI-G00-1767 |
A Randomized, Multicenter Phase III Clinical Trial of Pemetrexed and Cisplatin Versus Cisplatin Alone In Chemonaive Patients with Malignant Pleural Mesothelioma |
| E-E4802, ECOG-E4802 |
A Multicenter Phase II Clinical Trial of Pemetrexed and Gemcitabine in Patients with Chemotherapy-Naive, Advanced Cancer of the Urothelium |
| CALGB-90206, CDR0000335292, CAN-NCIC-CLB-90206 |
A Two-Arm, Phase III Trial Of Bevacizumab in Combination with Interferon Alfa-2B in Patients with Advanced Renal Carcinoma |
| UCCRC-11046A, NCI-2710 |
A Phase II Clinical Trial of Gemcitabine and Cisplatin with or Without Bevacizumab in Patients with Malignant Mesothelioma |
| OSU-01H0185, NCI-2669 |
A Randomized, Multicenter, Phase II Clinical Trial of Bevacizumab with or Without Interferon Alfa in Patients with Metastatic Malignant Melanoma |
| CDR0000271225, MDA-ID-02063, NCI-4772 |
A Randomized, Phase II Trial of Bevacizumab and PEG-Interferon Alfa-2b in Patients with Metastatic or Unresectable Carcinoid Tumors |
| UPCC-03903, NCI-6006, CDR0000343804 |
A Dose-Escalation, Open-Label, Phase I/II Clinical Trial of Bevacizumab and Imatinib Mesylate in Patients with Advanced Melanoma or Other Advanced Cancers |
| NSABP-C-08 |
A Randomized Phase III Clinical Trial of Adjuvant Chemotherapy Consisting of Fluorouracil, Leucovorin Calcium, and Oxaliplatin with or Without Bevacizumab in Patients with Resected Stage II or III Adenocarcinoma of the Colon |
| MDA-2004-0342, NCI-6484 |
A Randomized Phase II Clinical Trial of Idarubicin and Cytarabine with or Without Bevacizumab in Patients with Newly Diagnosed Acute Myeloid Leukemia |
| 04-033, MSKCC-04033 |
An Phase I/II Clinical Trial of Fixed Doses of Daily Gefitinib with Escalating Doses of Daily Everolimus In Advanced Non-Small Cell Lung Cancer |
| ECOG-E3303 |
A Multicenter, Phase II Clinical Trial of Cetuximab, Cisplatin, and Definitive Radiotherapy in Patients with Unresectable Locally Advanced or Regional Stage IV Squamous Cell or Undifferentiated Carcinoma of the Head and Neck |
| RTOG-0320 |
A Randomized, Multicenter, Phase III Clinical Trial of Whole Brain Radiotherapy and Stereotactic Radiosurgery with Versus Without Temozolomide or Gefitinib in Patients with Non-Small Cell Lung Cancer and Brain Metastases |
| UCHSC-01460, NCI-4551 |
A Multicenter, Dose-Escalation, Phase I Clinical Trial of Gefitinib in Combination with Radiotherapy with or Without Cisplatin in Patients with Previously Untreated, Locally Advanced Squamous Cell Carcinoma of the Head and Neck |
| PBTC-007 |
A Multicenter, Dose-Escalation, Phase II Clinical Trial of Gefitinib in Combination with Radiation Therapy in Children with Newly Diagnosed Glioma |
| CA225081 |
A Non-Randomized, Open-Label, Uncontrolled, Phase II Clinical Trial of Carboplatin and Cetuximab in Previously Untreated Patients with Stage IIIb/IV Non-Small Cell Lung Cancer |
| CA225058 |
A Randomized, Open-Label, Dose-Comparison, Phase II Clinical Trial of Two Dose Schedules of Carboplatin, Paclitaxel, and Cetuximab in Previously Untreated Patients with Stage IIIb/IV Non-Small Cell Lung Cancer |
| PRA-OSI2950g, GENENTECH-OSI2950g, UCLA-0408116-01 |
A Randomized, Placebo-Controlled, Double-Blind (for Arms I and II), Phase II Clinical Trial of Bevacizumab with Either Docetaxel or Erlotinib Versus Docetaxel Alone in Patients with Recurrent or Refractory Stage IIIb or IV Non-Small Cell Lung Cancer |
| JHOC-20020723; NCI-5375, CDR0000257942 |
A Multicenter, Dose-Escalation, Phase I Clinical Trial of Erlotinib and Radiotherapy with or Without Cisplatin in Treating Stage II, III, or IV Squamous Cell Carcinoma of the Oral Cavity or Oropharynx |
| ID02-327 |
A Phase II Clinical Trial of Erlotinib in Combination with Standard Chemotherapy (Carboplatin And Paclitaxel) Before Surgery in the Treatment of Non-Small Cell Lung Cancer. |
| COG-ADVL0214, CDR0000350336 |
A Phase I Clinical Trial of Erlotinib and Temozolomide in Children with Recurrent or Refractory Solid Tumors |
| UCDCC#128 |
A Phase I/II Clinical Trial of Docetaxel and Erlotinib in Patients with Advanced Solid Tumors with an Emphasis on Non-Small Cell Lung Cancer |
| 040256, 04-C-0256 |
A Phase I Clinical Trial of Erlotinib Followed by Erlotinib with Temozolomide in Patients with Selected Recurrent/Refractory Solid Tumors |
| ECOG-E4203 |
A Randomized, Multicenter, Phase II Clinical Trial of Bevacizumab and Oxaliplatin Combined with Irinotecan Versus Leucovorin Calcium and Fluorouracil in Patients with Previously Untreated Metastatic or Locally Recurrent Colorectal Adenocarcinoma |
| 03114 |
A Phase II Clinical Trial of Oxaliplatin, Capecitabine, and Bevacizumab in Patients with Metastatic Colorectal Cancer |
| ROCHE-BO16216, CWRU-030118, GENENTECH-H2223g, ROCHE-1100, ROCHE-B016216E, NCT00022672 |
A Randomized, Open-Label, Multicenter, Phase II/III Clinical Trial of Anastrozole with or Without Trastuzumab in Postmenopausal Women with Hormone-Receptor Positive, HER2-Overexpressing, Metastatic Breast Cancer |
| NCCTG-N0337, NCT00093808 |
A Multicenter Phase II Clinical Trial of Capecitabine, Vinorelbine and Trastuzumab as a First or Second-Line Treatment in Patients with HER2/Neu-Overexpressing Metastatic Breast Cancer |
| EORTC-10995, EORTC-16999, NCT00036868, IDBBC-EORTC-10995 |
A Phase II Clinical Trial of Cyclophosphamide, Methotrexate, Fluorouracil, and Trastuzumab in Women with HER2/Neu-Positive Metastatic Breast Cancer |
| FCCC-03041, NOVARTIS-FCCC-03041, NCT00084513 |
A Dose-Escalation, Phase I Clinical Trial of Trastuzumab and Imatinib Mesylate in Patients with Recurrent or Metastatic HER2/Neu-Overexpressing Cancer |
| UCLA-0407057-01, ZENECA-IRUSIRES0281 |
A Phase I/II Clinical Trial of Gefitinib and Sirolimus in Patients with Recurrent or Refractory Stage IIIb Or IV Non-Small Cell Lung Cancer |
| D7919C00706 |
A Randomized, Double-Blind, Placebo Controlled, Phase II Clinical Trial of Gefitinib in Patients with Previously Untreated Head and Neck Squamous Cell Carcinoma |
| CTRC-IDD-0332, NCI-6588 |
A Randomized, Phase I/II Clinical Trial of Erlotinib and Cetuximab with or Without Bevacizumab in Patients with Metastatic or Unresectable Renal Cell, Colorectal, Head and Neck, or Non-Small Cell Lung Cancer |
| RPCI-I-19903, GENENTECH-RPCI-I-19903 |
An Open-Label, Phase II Clinical Trial of Gemcitabine, Capecitabine, and Bevacizumab in Patients with Metastatic or Unresectable Adenocarcinoma of the Pancreas |
| NYWCCC-1004-528, NCI-6490 |
A Phase II Clinical Trial of Oxaliplatin, Fluourouracil, Leucovorin Calcium, Bevacizumab, and Cetuximab in Patients with Unresectable Stage IV Colorectal Cancer |
| GOG-0076DD, BMS-CA225-075 |
A Multicenter, Phase II Clinical Trial of Cetuximab and Cisplatin in Patients with Advanced, Persistent, or Recurrent Carcinoma of the Cervix |
| ECOG-E1B03 |
A Randomized, Multicenter, Phase II Clinical Trial of Pemetrexed Combined with Either Gemcitabine or Carboplatin in Patients with Advanced Malignant Mesothelioma of the Pleura |
| 9439 |
A Phase I/II Clinical Trial of Gemcitabine and Cisplatin Followed by Pemetrexed and Gemcitabine in Patients with Advanced or Metastatic Bladder Cancer |
| NO17629, NCT00089479 |
A Phase III Clinical Trial of Doxorubicin With Cyclophosphamide Followed by Docetaxel Alone or With Capecitabine as Adjuvant Therapy in Female Patients With High-Risk Breast Cancer |
| DUMC03, NCT00090610 |
A Phase III Clinical Trial of Docetaxel and Carboplatin as a Second-Line Treatment in Patients With Platinum-Sensitive Ovarian Cancer |
| NSABP-B-38, NCT00093795 |
A Randomized, Multicenter, Phase III Clinical Trial of 3 Different Adjuvant Chemotherapy Regimens Including Docetaxel, Doxorubicin and Cyclophosphamide, or Dose-Dense Doxorubicin, Cyclophosphamide, and Paclitaxel, or Dose-Dense Doxorubicin, Cyclophosphamide, Paclitaxel and Gemcitabine in Women With Node-Positive Breast Cancer |
| DOXIL-BCA-3001, NCT00091442 |
A Randomized, Parallel-Group, Open-Label, Phase III Clinical Trial of Docetaxel Alone or in Combination With Doxorubicin in Patients With Recurrent, Advanced Breast Cancer Who Were Administered Anthracycline in the Adjuvant or Neoadjuvant Setting |
| DFCI-04006, AVENTIS-DFCI-04006, NCT00095875 |
A Randomized Phase III Clinical Trial of Induction Chemotherapy Comprising of Docetaxel, Cisplatin, and Fluorouracil Followed by Radiotherapy and Carboplatin or Docetaxel Versus Radiotherapy and Cisplatin Only in Patients With Previously Untreated Stage III or IV Squamous Cell Carcinoma of the Head and Neck |
| SWOG-S0016, NCT00006721, CALGB-50102 |
A Randomized Phase III Clinical Trial of Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone Combined With Either Rituximab or Tositumomab |
| SWOG-S0347, NCT00103233 |
A Randomized Phase III Clinical Trial of Vinorelbine With and Without Trastuzumab in Women With HEr2 Positive Progressive Metastatic Breast Cancer |
| 8426 |
A Phase II Clinical Trial of Pemetrexed With Doxorubicin in Patients With Advanced Breast Cancer |
| EORTC-08013, EUDRACT-2004-001332-23, NCT00103051 |
An Open-Label, Nonrandomized, Multicenter, Phase II Clinical Trial of Neoadjuvant Induction Therapy Comprising of Gemcitabine, Cisplatin, and Gefitinib in Patients With Stage IIIa Non-Small Cell Lung Cancer Undergoing Surgery |
| MUSC-031218, MUSC-HR-11357, NCT00103376 |
A 2-Part, Open-Label, Phase II Clinical Trial of Bortezomib With or Without Combined Androgen Blockade Therapy in Patients With Early Relapsed Adenocarcinoma of the Prostate |
| SWOG-S0124, CTSU, NCT00045162, CALGB-S0124, NCCTG-S0124 |
A Randomized Phase III Clinical Trial of Cisplatin and Irinotecan Versus Cisplatin and Etoposide in Patients With Extensive Stage, Small Cell Lung Cancer |
| FFCD-EORTC-40012, EORTC-40012, PETACC-4, NCT00091312 |
A Randomized Phase III Clinical Trial of Fluorouracil and Irinotecan With or Without Leucovorin Calcium Compared to no Adjuvant Therapy in Patients With Resected, Stage II Adenocarcinoma of the Colon |
| NO16967, NCT00069108 |
A Phase III Clinical Trial of Capecitabine in Combination With Oxaliplatin (XELOX) Compared to Fluorouracil in Combination With Leucovorin and Oxaliplatin (FOLFOX4) in Patients With Metastatic Colorectal Cancer Who Have Previously Been Administered Irinotecan in Combination With Fluorouracil and Leucovorin |
| L_9210, NCT00087802 |
A Phase III Clinical Trial of Gemcitabine and Oxaliplatin Compared to Carboplatin and Paclitaxel in Patients With Advanced, Non-Small Cell Lung Cancer |
| GOG-9918 |
A Dose-Escalation, Multicenter, Phase I Clinical Trial of Cetuximab in Combination With Cisplatin, External Beam Radiotherapy and Brachytherapy in Patients With Stage Ib-IVa Cervical Cancer |
| A5961065 |
An Open Label, Non-Randomized, Phase IV Clinical Trial of Irinotecan in Combination With 5-FU, Leucovorin And Bevacizumab in Patients With Colorectal Carcinoma That Has Spread to the Liver Only and is Currently Not Able to be Removed by Surgery |
| RPCI-I-22204, GENENTECH-RPCI-I-22204 |
An Open Label Phase II Clinical Trial of Bevacizumab and Capecitabine as a First-Line Treatment in Older Patients With Metastatic Colorectal Cancer |
| TUGSM-UHA-BC03-01, NCT00107393 |
A Phase II Clinical Trial of Trastuzumab and Capecitabine in Patients With Taxane and Anthracycline-Refractory, HEr2/Neu Overexpressing, Metastatic Breast Cancer |
| CDR0000416124; FRE-FNCLCC-GETUG-13/0206; EU-20502; NCT00104676 |
A Randomized Phase III Clinical Trial of Bleomycin, Etoposide, and Cisplatin With or Without Dose-Dense Sequential Combination Chemotherapy (Paclitaxel, Oxaliplatin, And Ifosfamide) in Patients With Poor Prognosis Stage II or III Non-Seminomatous Germ Cell Tumors |
| COG-AOST0121 |
A Multicenter Phase II Clinical Trial of Trastuzumab And Chemotherapy in Patients With HEr2-Overexpressing Metastatic Osteosarcoma |
| SWS-SAKK-22/99; EU-99028 |
A Randomized Multicenter Phase III Trial of Trastuzumab With or Without Paclitaxel in Treating Women With Metastatic Breast Cancer That Overexpresses HEr2 |
| CLB-49903 |
A Randomized Phase III Clinical Trial of Trastuzumab With or Without Tamoxifen in Treating Women With Invasive Stage IV Breast Cancer. |
| NCCTG-N0531 |
A Multicenter Phase II Clinical Trial Of Nanoparticle Albumin-Bound Paclitaxel (Abraxane, ABI-007) And Gemcitabine In Women With Metastatic Breast Cancer |
| MSKCC-04018, ABI-CA016, NCT00085605, CA016-0 |
An Open Label, Phase II Clinical Trial of Nanoparticle Albumin-Bound Paclitaxel (Abraxane, ABI-007), Carboplatin and Trastuzumab in Patients With Her2/Neu-Overexpressing Metastatic Breast Cancer |
| CALGB-90401, NCT00110214 |
A Randomized, Double Blind, Placebo Controlled, Multicenter Phase III Clinical Trial of Docetaxel and Prednisone With Versus Without Bevacizumab in Patients With Hormone-Refractory Metastatic Adenocarcinoma of the Prostate |
| SWOG-S0414, NCT00109850 |
A Multicenter Phase II Clinical Trial of Cetuximab, Cisplatin, Irinotecan and Thoracic Radiotherapy in Patients With Previously Untreated, Clinically Inoperable, Locally Advanced Squamous Cell Carcinoma or Adenocarcinoma of the Esophagus |
| CA225-085 |
A Phase I Clinical Trial of Cetuximab in Combination With Irinotecan in Pediatric and Adolescent Patients With Refractory Solid Tumors |
| 2003-1049 |
A Phase I Clinical Trial of Erlotinib and Docetaxel With Concomitant Boost Radiation Therapy in Patients With Locoregionally Advanced Head and Neck Squamous Cell Carcinoma |
| 2003-0982 |
A Non-Randomized, Open Label Phase II Clinical Trial of Neoadjuvant Erlotinib and Bevacizumab In Patients With Metastatic, Clear Cell Renal Cell Carcinoma |
| UCLA-0412086-01, ROCHE-BO17920A |
A Randomized, Open Label, Multicenter Phase III Clinical Trial of Adjuvant Oxaliplatin, Leucovorin Calcium and Fluorouracil (FOLFOX-4) Compared to Bevacizumab and FOLFOX-4 Compared to Bevacizumab, Oxaliplatin and Capecitabine in Patients With High-Risk Stage II or III Colon Cancer |
| NCCTG-N034A |
A Multicenter Phase II Clinical Trial of Bevacizumab, Gemcitabine and Oxaliplatin in Patients With Metastatic Adenocarcinoma of the Pancreas |
| 2003-0832 |
A Non Randomized, Open Label Phase II Clinical Trial of Neoadjuvant Concurrent Capecitabine, Bevacizumab and Radiotherapy in Patients Presenting With Locally Advanced Rectal Cancer |
| CA225-099 |
A Phase II Clinical Trial Of a Taxane and Carboplatin With or Without Cetuximab as a First-Line Treatment for Patients With Advanced or Metastatic Non-Small Cell Lung Cancer |
| CA225-100 |
A Phase II Clinical Trial of Gemcitabine and Platinum With or Without Cetuximab as a First-Line Treatment for Patients With Advanced or Metastatic Non-Small Cell Lung Cancer |
| MCC 13726 |
A Phase II Clinical Trial of Neoadjuvant Chemotherapy With Gemcitabine and Pemetrexed in Operable Non-Small Cell Lung Cancer |
| RTOG-0411, NCT00114179 |
A Phase II Clinical Trial of Capecitabine, Bevacizumab, and Radiotherapy Followed by Maintenance Therapy Comprising Gemcitabine and Bevacizumab in Patients With Inoperable Locally Advanced Pancreatic Cancer |
| NSABP FB-AX-003, NCT00110695 |
A Non Randomized Phase II Clinical Trial of Nanoparticle Albumin Bound Paclitaxel (ABI-007, Abraxane) in Combination With 5-Fluorouracil, Epirubicin and Cyclophosphamide in Women With Locally Advanced Breast Cancer |
| RTOG-0412, NCT00113386, SWOG-S0332 |
A Randomized, Multicenter Phase III Clinical Trial of Neoadjuvant Cisplatin and Docetaxel With Versus Without Thoracic Conformal Radiotherapy Followed by Surgical Resection and Docetaxel in Patients With Newly Diagnosed Favorable Prognosis Stage IIIa Non-Small Cell Lung Cancer |
| RTOG-0421, ECOG-R0421, NCT00113399 |
A Randomized Phase III Clinical Trial of Radiotherapy, Cisplatin and Paclitaxel Compared to Cisplatin-Based Chemotherapy Alone (With Fluorouracil, Paclitaxel, or Docetaxel) In Patients With Previously Irradiated, Inoperable, Locally Recurrent Squamous Cell Carcinoma of the Head And Neck |
| 01-2003, MO17728 |
A Randomized, Open Label Phase III Clinical Trial of Docetaxel Followed by Cyclophosphamide, Epirubicin and 5-Fluorouracil (CEF) Compared to Docetaxel and Capecitabine Followed by Cyclophosphamide, Epirubicin and Capecitabine (CEX) as Adjuvant Treatment for Early Breast Cancer With an Intermediate-To-High Risk of Cancer Recurrence |
| FRE-FNCLCC-ACCORD-11/0402, EU-20512, NCT00112658 |
A Randomized Phase II/III Clinical Trial of Oxaliplatin, Irinotecan, Leucovorin Calcium and 5-Fluorouracil Compared to Gemcitabine as a First-Line Therapy in Patients With Metastatic Adenocarcinoma of the Pancreas |
| CASE-2204, CWRU-100450, OSI-CASE-2204 |
A Phase I Clinical Trial of Erlotinib Followed by Oxaliplatin, Leucovorin Calcium and Fluorouracil (Modified FOLFOX6) as First-Line Therapy in Patients With Metastatic Colorectal Cancer |
| 04-365 |
A Non-Randomized, Open Label Phase II Clinical Trial of Bevacizumab and Erlotinib in Combination With Fluorouracil, Leucovorin and Oxaliplatin (FOLFOX) in Patients With Previously Untreated, Metastatic Colorectal Cancer |
| CALGB-30306 |
A Phase II Clinical Trial of Cisplatin, Irinotecan and Bevacizumab in Patients With Extensive Stage Small Cell Lung Cancer |
| SWOG-S0408, ECOG-SWOG-S0408 |
A Multicenter Phase II Clinical Trial of Neoadjuvant Capecitabine, Oxaliplatin, and Bevacizumab in Patients With Operable Hepatic Metastases Secondary to Colorectal Cancer |
| ECOG-E2104 |
A Multicenter Phase II Clinical Trial of Adjuvant Bevacizumab and Dose Dense Doxorubicin and Cyclophosphamide Followed by Paclitaxel in Patients With Resected Lymph Node-Positive Breast Cancer |
| CALGB-30402 |
A Randomized, Multicenter Phase II Clinical Trial of Docetaxel in Combination With Either Cetuximab or Bortezomib as a First-Line Therapy in Patients With Stage IIIb or IV, Performance Status 2 Non-Small Cell Lung Cancer |
| CALGB-30407 |
A Randomized, Multicenter Phase II Clinical Trial of Pemetrexed Disodium, Carboplatin, and Thoracic Radiotherapy With or Without Cetuximab in Patients With Inoperable, Stage III Non-Small Cell Lung Cancer |
| NEAR L-284/2004 |
A Non-Randomized, Open Label Phase II Clinical Trial of Cetuximab in Combination With Locoregional Radiotherapy in Patients With Inoperable, Stage III Non-Small Cell Lung Cancer |
| IRB 6320 |
A Phase II Clinical Trial of Erlotinib With Temozolomide and Concurrent Radiation Therapy in Patients With Newly-Diagnosed Glioblastoma Multiforme |
| |
A Phase II Clinical Trial of Erlotinib in Combination With Capecitabine in Patients With Advanced, Metastatic Pancreatic Cancer Who Failed First-Line Gemcitabine-Based Therapy |
| UNKPRI 15 |
A Phase II Clinical Trial of Bevacizumab and Erlotinib in Patients With Metastatic Carcinoma of Unknown Primary Site |
| |
A Randomized Phase III Trial of Adjuvant Chemotherapy With Cisplatin and Vindesine Followed by UFT for Completely Resected Pathologic Stage IIIa-N2 Non-Small Cell Lung Cancer (NSCLC)-West Japan Study Group for Lung Cancer Surgery (WJSG) |
| |
Phase I/II Study of Weekly Paclitaxel, UFT and Leucovorin in Patients with Metastatic Breast Cancer |
| |
A Phase II Trial of Adjuvant Chemotherapy with Weekly Paclitaxel and Carboplatin Followed by UFT for Completely Resected Pathologic Stage II and IIIA Non-Small Cell Lung Cancer (NSCLC) |
| |
A Multicenter, Phase II Clinical Trial of Oxaliplatin, Uracil/Tegafur and Radiotherapy in Patients with Operable Rectal Cancer |
| ECOG 1299 |
A Phase II Study of Orzel (UFT+Leucovorin) in Elderly Patients with Colorectal Cancer |
| SWOG-S0515 |
A Phase II Clinical Trial of Cyclophosphamide, Doxorubicin, Vincristine, Prednisone (CHOP) and Rituximab in Combination With Bevacizumab in Older Patients With Bulky Stage II or Stage III or IV Diffuse Large B-Cell Lymphoma |
| |
A Phase I Trial of Low Dose Cisplatin, UFT, Diethylstilbestrol, and Dexamethasone (CUDD) for Patients with HRPC |
| GOC-GI-010 |
A Non-Randomized, Uncontrolled Phase II Clinical Trial of Oxaliplatin, Capecitabine and Bevacizumab in Older Patients with Colorectal Cancer |
| |
A Multicenter Phase II Study of Adjuvant Bi-Weekly Irinotecan , Infusional 5-Fluorouracil (5FU) and Leucovorin (LV) with Oral Tegafur/Uracil (UFT) Following Resection of Colorectal Hepatic Metastases |
| 05-055, NCT00121134 |
A Non-Randomized, Open Label Phase II Clinical Trial of Bevacizumab With or Without Cyclophosphamide and Methotrexate in Women With Operable Breast Cancer |
| ML18527 |
A Phase IV Clinical Trial of Cepecitabine and Bevacizumab in Previously Untreated Patients With HEr2-Negative, Metastatic Breast Cancer Followed by Chemotherapy (Paclitaxel or Vinorelbine) Combined With Bevacizumab if Disease Progresses |
| ML18491 |
A Phase IV Clinical Trial of 2 Different Treatment Schedule of Intermittent Capecitabine and Oxaliplatin Combined With Bevacizumab as First-Line Treatment in Patients With Metastatic Colorectal Cancer |
| |
An Open, Multi Center, Phase II Clinical Trial to Evaluate Efficacy and Safety of Paclitaxel, UFT, and Leucovorin in Patients with Advanced Gastric Cancer |
| |
A Multicenter Phase II Trial of Pre-Administrated UFT Plus Gemcitabine for Unresectable/Recurrent Pancreatic Cancer |
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UFT After Sequential Chemo and Radiotherapy in Patients with Stage IIIb Non-Small Cell Lung Cancer |
| CINJ-040412, CINJ-5191, CINJ-NJ1104, NCT00118053 |
A Non Randomized, Multicenter Phase II Clinical Trial of Trastuzumab, Docetaxel and Carboplatin in Women With Previously Untreated, HEr2/Neu-Positive, Stage IIb, IIIa, IIIb Or IIIc, or Inflammatory Breast Cancer |
| |
A Randomized Controlled Study Comparing cyclophosphamide, methotrexate, and 5-Fluorouracil Plus Tamoxifen with UFT Plus Tamoxifen as Postoperative Adjuvant Therapy in Women with Node-Positive Breast Cancer |
| |
A Phase III Trial of Adjuvant Chemotherapy with UFT for Serosa Negative Advanced Gastric Cancer |
| EMR 62202-002 |
A Randomized, Open Label Phase III Clinical Trial of Cetuximab in Combination With Cisplatin or Carboplatin and 5-Fluorouracil Compared to Cetuximab Alone in The First Line Treatment of Patients With Recurrent and/or Metastatic Squamous Cell Carcinoma of the Head and Neck |
| |
PhaseI/II Study of Paclitaxel, Carboplatin and UFT in Chemo-Naive Patients with Advanced Non-Small Lung Cancer |
| |
Randomized Controlled Trial of Gemcitabine in Combination with UFT Versus Gemcitabine Alone in Patients with Advanced Pancreatic Cancer |
| |
A Combination of Oxaliplatin and UFT-L,-Leucovorin as First Line Treatment in Advanced Colorectal Cancer-an Oncopaz Phase II Study. |
| |
Adjuvant Oral UFT Improves Survival After Complete Mesorectal Excision or Pathologic Tumor, Nodes, Metastases Stage III Rectal Cancer |
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A Phase I Trial of UFT And Oral Leucovorin + Weekly Oxaliplatin and Preoperative Radiotherapy In Locally Advanced Rectal Cancer |
| NSABP Protocol C-06 |
A Phase III Trial Comparing Oral UFT with Leucovorin to 5-FU with Leucovorin (FULV) in Stage II and III Carcinoma of the Colon |
| CALGB-50303, ECOG-50303, NCT00118209 |
A Randomized Phase III Clinical Trial of Rituximab, Cyclophosphamide, Doxorubicin, Vincristine and Prednisone (R-CHOP) Compared to Etoposide, Prednisone, Vincristine, Cyclophosphamide, Doxorubicin, and Rituximab (EPOCH-R) in Patients With Previously Untreated, De Novo, Diffuse, Large B-Cell Non-Hodgkin’s Lymphoma |
| BMTCTN-0202, FMLH-04-143, HRRC-301-04, NCT00096460 |
A Phase II/III Clinical Trial of Autologous Hematopoietic Stem Cell Transplantation (HSCT) or Non-Myeloablative Allogeic HSCT from a HLA-Matched Sibling Donor in Patients with Recurrent Grade I or II Follicular Non-Hodgkin’s Lymphoma |
| SWOG-S9704, NCT00004031, CALGB-59903, CAN-NCIC-LY11, ECOG-S9704 |
A Randomized Phase III Clinical Trial of Early High-Dose Chemoradiotherapy and Autologous Peripheral Blood Stem Cell Transplantation Compared to Conventional Dose Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (CHOP) in Patients with Intermediate- or High-Grade Non-Hodgkin's Lymphoma |
| MSKCC-03139, CORAL-50-03B, NCT00081146 |
A Randomized, Open Label, Multicenter Phase III Clinical Trial of Rituximab, Ifosfamide, Carboplatin, and Etoposide Compared to Rituximab, Dexamethasone, Cytarabine, and Cisplatin as Induction Therapy Followed by High-Dose Consolidation Chemotherapy and Autologous Stem Cell Transplantation With Versus Without Rituximab as Maintenance Therapy in Patients With Relapsed or Refractory CD20-Positive Diffuse Large B-Cell Non-Hodgkin's Lymphoma |
| |
A Dose Finding Phase I Trial Followed By a Phase II Trial of Oral UFT and Leucovorin Plus IV Mitomycin in Patients with Metastatic Colorectal Cancer |
| IRB 13362B |
A Randomized, Open Label, Phase III Clinical Trial of Induction Therapy with Docetaxel Followed by Chemoradiotherapy Versus Chemoradiotherapy Alone in Patients with Locally Advanced, Head and Neck Cancer |
| 05-043 |
A Randomized, Open Label Phase III Clinical Trial of Androgen Suppression and Radiation Therapy for 6 Months With or Without Docetaxel in Men With High Risk Localized or Locally Advanced Prostate Cancer |
| NO16853 |
A Phase III Clinical Trial of Capecitabine With or Without Docetaxel in Patients With Locally Advanced or Metastatic Breast Cancer After Failure of Chemotherapy With Anthracycline |
| |
A Phase I Clinical Trial of Gefitinib, Oxaliplatin, 5-Fluorouracil and Leucovorin in Patients With Advanced Solid Malignancies |
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A Multicenter Phase II Trial of BiWeekly Irinotecan, Infusional 5-Fluorouracil and Leucovorin with Oral UFT for Metastatic Colorectal Cancer |
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A Phase I/II Study of Tegafur-Uracil (UFT) Plus Oral Leucovorin and Biweekly Irinotecan Therapy For Patients with Metastatic Colorectal Cancer |
| EORTC-40986 |
A Phase III Clinical Trial of Weekly High-Dose Infusional Fluourouracil and Folinic Acid With or Without Irinotecan in Patients With Metastatic Colorectal Cancer |
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A Phase II Trial of High Dose Radiotherapy and UFT/Leucovorin in Patients with Locally Advanced Rectal Cancer |
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Docetaxel, Cisplatin, UFT and Leucovorin Combination Chemotherapy in Advanced Gastric Cancer |
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Oxaliplatin, UFT and Oral Leucovorin Combination Chemotherapy in Patients with 5-Fluorouracil Refractory Colorectal Carcinoma |
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Pilot Trial of Irinotecan and Thalidomide in Patients with Advanced Cancer |
| |
A Randomized Phase III Clinical Trial of the Irinotecan, Leucovorin, And Fluorouracil Regimen (FOLFIRI) Compared to the Oxaliplatin, Leucovorin, and Fluorouracil Regimen (FOLFOX4) in Previously Untreated Patients With Advanced Colorectal Cancer |
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Phase II Study of a Fixed Dose Rate Infusion of Gemcitabine Associated to Cisplatin and UFT in Advanced Carcinoma of the Pancreas |
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Phase II Study of Vinorelbine and UFT in Patients with Metastatic Breast Cancer Previously Treated with Anthracyclines and Taxanes |
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Preoperative Radiation and Daily Oral UFT in Combination with Leucovorin In Locally Advanced Rectal Cancer |
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Combination Study of UFT with Leucovorin and Oxaliplatin as First Line Treatment for Patients with Nonresectable Metastatic Colorectal Cancer |
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A Phase II Trial of Oxaliplatin and UFT with Folinic Acid for Advanced Colorectal Cancer in Elderly Patients |
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