February 2010 Targets in Oncology Updates and Additions

Androgen receptor (Ar) CREB regulated transcription coactivator 2 (CRTC2) Cyclin D binding myb-like transcription factor 1 (DMTF1) Dickkopf (DKK) family Heat shock 70kDa protein 5 (HSPA5) Histone deacetylase 6 (HDAC6) Hypoxia inducible factor 1 alpha (HIF1A) Lamin A/C (LMNA) Mixed lineage leukemia (MLL) Myeloid differentiation primary response gene 88 (MyD88) Oncostatin M (OSM) Seven in absentia homolog-1 (SIAH1) Toll-like receptor 9 (TLr9) V-raf murine sarcoma viral oncogene homolog B1 (BRAF)